Activation of L-lactate oxidase by the formation of enzyme assemblies through liquid–liquid phase separation

Abstract The assembly state of enzymes is gaining interest as a mechanism for regulating the function of enzymes in living cells. One of the current topics in enzymology is the relationship between enzyme activity and the assembly state due to liquid–liquid phase separation. In this study, we demons...

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Bibliographic Details
Main Authors: Tomoto Ura, Ako Kagawa, Nanako Sakakibara, Hiromasa Yagi, Naoya Tochio, Takanori Kigawa, Kentaro Shiraki, Tsutomu Mikawa
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28040-1