A mouse pancreatic organoid model to compare PD-L1 blocking antibodies

A mouse pancreatic organoid model to compare PD-L1 blocking antibodies

Immune checkpoint inhibitors (ICIs) have changed the therapeutic landscape for cancer patients, but diabetes, a rare, severe immune-related endocrinopathy, is linked to ICI therapy. It is unclear whether glycosylation of ICIs may play a role in the development of this adverse event and how the physi...

Full description

Bibliographic Details
Main Authors: Guangyuan Li, Susmita Ghosh, JuMe Park, Hyunsu Shin, Mamatha Garige, Gregory Reaman, Carole Sourbier
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:mAbs
Subjects:
Immune checkpoint inhibitors
PD-L1
diabetes
metabolism
pancreatic organoids
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2022.2139886

Internet

https://www.tandfonline.com/doi/10.1080/19420862.2022.2139886

Similar Items