Lumican binds ALK5 to promote epithelium wound healing.

Lumican (Lum), a small leucine-rich proteoglycan (SLRP) family member, has multiple matricellular functions both as an extracellular matrix component and as a matrikine regulating cell proliferation, gene expression and wound healing. To date, no cell surface receptor has been identified to mediate...

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Bibliographic Details
Main Authors: Osamu Yamanaka, Yong Yuan, Vivien Jane Coulson-Thomas, Tarsis Ferreira Gesteira, Mindy K Call, Yujin Zhang, Jianhua Zhang, Shao-Hsuan Chang, Changchun Xie, Chia-Yang Liu, Shizuya Saika, James V Jester, Winston W-Y Kao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867403?pdf=render