Protein Engineering of <i>Pasteurella multocida</i> α2,3-Sialyltransferase with Reduced α2,3-Sialidase Activity and Application in Synthesis of 3′-Sialyllactose
Sialyltransferases are key enzymes for the production of sialosides. The versatility of <i>Pasteurella multocida</i> α2,3-sialyltransferase 1 (PmST1) causes difficulties in the efficient synthesis of α2,3-linked sialylatetd compounds, especial its α2,3-sialidase activity. In the current...
Main Authors: | Rui Yang, Mengge Gong, Siming Jiao, Juntian Han, Cui Feng, Meishan Pei, Zhongkai Zhou, Yuguang Du, Jianjun Li |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
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Series: | Catalysts |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4344/12/6/579 |
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