Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers

Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers

Purpose: We present a case of bilateral extensive peripapillary myelinated retinal nerve fibers (MRNF) in an individual with Crouzon syndrome, an inherited form of craniosynostosis caused by overactivation of fibroblast growth factor receptor 2. As a secondary aim, we examine the utility of optical...

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Bibliographic Details
Main Authors: Giancarlo A. Garcia, Jack J. Tian, Supanut Apinyawasisuk, Sarah Kim, Handan Akil, Alfredo A. Sadun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-12-01
Series:Journal of Current Ophthalmology
Subjects:
Myelin
Myelinated retinal nerve fibers
Crouzon syndrome
Fibroblast growth factor receptor
Optical coherence tomography angiography
Online Access:http://www.sciencedirect.com/science/article/pii/S2452232516301299

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http://www.sciencedirect.com/science/article/pii/S2452232516301299

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