Sodium-glucose cotransporter 2 inhibition and health benefits: The Robin Hood effect

Sodium-glucose cotransporter 2 inhibition and health benefits: The Robin Hood effect

This review discusses two distinct, yet related, mechanisms of sodium-glucose cotransporter 2 (SGLT2) inhibition: Calorie restriction mimicry (CRM) and pro-ketogenic effect, which may explain their cardiovascular benefits. We term these adaptive CRM and pro-ketogenic effects of SGLT2 inhibition, the...

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Bibliographic Details
Main Authors: Sanjay Kalra, Arpit Jain, Jignesh Ved, A G Unnikrishnan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Calorie restriction mimicry canagliflozin
cardiovascular outcomes
dapagliflozin
diabetes
EMPA-REG outcome
empagliflozin
ketogenesis
ketogenic diet
liraglutide
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2016;volume=20;issue=5;spage=725;epage=729;aulast=Kalra

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http://www.ijem.in/article.asp?issn=2230-8210;year=2016;volume=20;issue=5;spage=725;epage=729;aulast=Kalra

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