Clec7a expression in inflammatory macrophages orchestrates progression of acute kidney injury

Acute kidney injury (AKI) is associated with high risk of mortality, post-disease renal fibrosis, kidney dysfunction and renal failure. Renal macrophages play a key role in the pathogenesis (M1 subpopulation), healing and remodeling (M2 subpopulation) in AKI and, thus, have been a promising target f...

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Bibliographic Details
Main Authors: Yaqiong Wang, Xianzhe Li, Xialian Xu, Jinbo Yu, Xiaohong Chen, Xuesen Cao, Jianzhou Zou, Bo Shen, Xiaoqiang Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1008727/full