Decoding the dual recognition mechanism of the glucocorticoid receptor for DNA and RNA: sequence versus shape

Abstract Transcription factors (TFs) regulate eukaryotic transcription through selective DNA-binding, can also specifically interact with RNA, which may present another layer of transcriptional control. The mechanisms of the TFs-DNA recognition are often well-characterised, while the details of TFs-...

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Bibliographic Details
Main Authors: Johanna Hörberg, Anna Reymer
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43244-1