Influence of single-nucleotide polymorphisms in TLR3 (rs3775291) and TLR9 (rs352139) on the risk of CMV infection in kidney transplant recipients

Influence of single-nucleotide polymorphisms in TLR3 (rs3775291) and TLR9 (rs352139) on the risk of CMV infection in kidney transplant recipients

Risk stratification for cytomegalovirus (CMV) infection after kidney transplantation (KT) remains to be determined. Since endosomal toll-like receptors (TLRs) are involved in viral sensing, we investigated the impact of common single-nucleotide polymorphisms (SNPs) located within TLR3 and TLR9 genes...

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Bibliographic Details
Main Authors: Natalia Redondo, Isabel Rodríguez-Goncer, Patricia Parra, Tamara Ruiz-Merlo, Francisco López-Medrano, Esther González, Natalia Polanco, Hernando Trujillo, Ana Hernández, Rafael San Juan, Amado Andrés, José María Aguado, Mario Fernández-Ruiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
cytomegalovirus
kidney transplantation
single-nucleotide polymorphism (SNP)
toll-like receptor 3 (TLR3)
toll-like receptor 9 (TLR9)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.929995/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.929995/full

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