Experimentally unsupervised deconvolution for light-sheet microscopy with propagation-invariant beams

We present experimentally unsupervised learned deconvolution for light-sheet microscopy using propagation-invariant beams. By training a generative adversarial network using simulated paired images consistent with the physics of the imaging system, and real unpaired experimental data, we create a ne...

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Bibliographic Details
Main Authors: Philip Wijesinghe, Stella Corsetti, Darren J. X. Chow, Shuzo Sakata, Kylie R. Dunning, Kishan Dholakia
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-022-00975-6