Altered Surface Expression of Insulin-Degrading Enzyme on Monocytes and Lymphocytes from COVID-19 Patients Both at Diagnosis and after Hospital Discharge

Although the COVID-19 disease has developed into a worldwide pandemic, its pathophysiology remains to be fully understood. Insulin-degrading enzyme (IDE), a zinc-metalloprotease with a high affinity for insulin, has been found in the interactomes of multiple SARS-CoV-2 proteins. However, the relevan...

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Bibliographic Details
Main Authors: Carlos M. González-Casimiro, Elisa Arribas-Rodríguez, Aida Fiz-López, Javier Casas, Sara Gutiérrez, Pablo Tellería, Cristina Novoa, Silvia Rojo-Rello, Eduardo Tamayo, Antonio Orduña, Carlos Dueñas, David Bernardo, German Perdomo
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/19/11070