Arene C–H borylation strategy enabled by a non-classical boron cluster-based electrophile

Electrophilic borylation of sterically hindered arenes is a challenging transformation. Here, authors report a metal-free electrophilic C–H borylation of hindered arenes using a boron cluster reagent producing valuable aryl boronic esters.

Bibliographic Details
Main Authors: Sangmin Kim, Joseph W. Treacy, Yessica A. Nelson, Jordan A. M. Gonzalez, Milan Gembicky, K. N. Houk, Alexander M. Spokoyny
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37258-6