Absorption, tissue distribution, and excretion of glycycoumarin, a major bioactive coumarin from Chinese licorice (Glycyrrhiza uralensis Fisch)

Absorption, tissue distribution, and excretion of glycycoumarin, a major bioactive coumarin from Chinese licorice (Glycyrrhiza uralensis Fisch)

Licorice (Glycyrrhiza uralensis Fisch) is a natural plant resource widely used as a food and herbal medication in China. Glycycoumarin (GCM) is a major coumarin in licorice that possesses several biological activities. However, little is known about its pharmacokinetic profile. The present study aim...

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Bibliographic Details
Main Authors: Linhu Ye, Lei Cheng, Yan Deng, Sen Wang, Xinyu Wu, Shuiping Ou, Qi Chang, Xinqian Zhao, Wen Zhou, Jinghua Yu, Zuqiang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pharmacology
Subjects:
glycycoumarin
pharmacokinetics
bioavailability
tissue distribution
LC-MS/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1216985/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1216985/full

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