Novel Role for Pleckstrin Homology‐Like Domain Family A, Member 3 in the Regulation of Pathological Cardiac Hypertrophy

Novel Role for Pleckstrin Homology‐Like Domain Family A, Member 3 in the Regulation of Pathological Cardiac Hypertrophy

Background Pleckstrin homology‐like domain family A, member 3 (PHLDA3), a crucial member of the PHLDA family, is involved in tumor suppression, kidney injury, liver injury, and glucose metabolism. However, the role of PHLDA3 in pathological cardiac hypertrophy and heart failure remains unclear. Meth...

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Bibliographic Details
Main Authors: Jia Liu, Xiaoxiong Liu, Xuejun Hui, Lin Cai, Xuebo Li, Yang Yang, Shangzhi Shu, Fan Wang, Hao Xia, Shuyan Li
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
AKT
cardiac hypertrophy
heart failure
pleckstrin homology‐like domain family A, member 3
pressure overload
signal transduction
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.011830

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.011830

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