Corneal Regeneration by Deep Anterior Lamellar Keratoplasty (DALK) Using Decellularized Corneal Matrix.

The purpose of this study is to demonstrate the feasibility of DALK using a decellularized corneal matrix obtained by HHP methodology. Porcine corneas were hydrostatically pressurized at 980 MPa at 10°C for 10 minutes to destroy the cells, followed by washing with EGM-2 medium to remove the cell deb...

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Main Authors: Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Jun Negishi, Takako Honda, Shinya Hattori, Kwangwoo Nam, Tsuyoshi Kimura, Manabu Mochizuki, Hisatoshi Kobayashi, Akio Kishida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4498638?pdf=render