Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003.

In the present study we show that luxS of Bifidobacterium breve UCC2003 is involved in the production of the interspecies signaling molecule autoinducer-2 (AI-2), and that this gene is essential for gastrointestinal colonization of a murine host, while it is also involved in providing protection aga...

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Bibliographic Details
Main Authors: Steven E A Christiaen, Mary O'Connell Motherway, Francesca Bottacini, Noreen Lanigan, Pat G Casey, Geert Huys, Hans J Nelis, Douwe van Sinderen, Tom Coenye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24871429/pdf/?tool=EBI