Ambra1 deficiency impairs mitophagy in skeletal muscle

Ambra1 deficiency impairs mitophagy in skeletal muscle

Abstract Background Maintaining healthy mitochondria is mandatory for muscle viability and function. An essential surveillance mechanism targeting defective and harmful mitochondria to degradation is the selective form of autophagy called mitophagy. Ambra1 is a multifaceted protein with well‐known a...

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Bibliographic Details
Main Authors: Lisa Gambarotto, Samuele Metti, Martina Chrisam, Cristina Cerqua, Patrizia Sabatelli, Andrea Armani, Carlo Zanon, Marianna Spizzotin, Silvia Castagnaro, Flavie Strappazzon, Paolo Grumati, Matilde Cescon, Paola Braghetta, Eva Trevisson, Francesco Cecconi, Paolo Bonaldo
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Ambra1
Skeletal muscle
Mitophagy
Mitochondria
Online Access:https://doi.org/10.1002/jcsm.13010

Internet

https://doi.org/10.1002/jcsm.13010

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