High-Dose Acetaminophen with <i>N</i>-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages

High-Dose Acetaminophen with <i>N</i>-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages

High-dose acetaminophen (AAP) with <i>N</i>-acetylcysteine (NAC) rescue is among the few treatments that has shown activity in phase I trials without achieving dose-limiting toxicity that has not progressed to evaluation in later line studies. While the anti-tumor effects of AAP/NAC appe...

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Bibliographic Details
Main Authors: Allyn Bryan, Pavani Pingali, Martha Joslyn, Howard Li, Tytus Bernas, Jennifer Koblinski, Joseph Landry, Won Sok Lee, Bhaumik Patel, Alexander Neuwelt
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
acetaminophen
breast cancer
tumor-associated macrophages
Online Access:https://www.mdpi.com/2072-6694/15/19/4770

Internet

https://www.mdpi.com/2072-6694/15/19/4770

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