Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop

The Ebola virus glycoprotein is a target for cross-protective antibodies. Here, Janus et al. report the crystal structure of the antigen-binding fragment of a pan-reactive antibody bound to a conserved epitope of the glycoprotein, facilitating rational design of cross-protective vaccines and therape...

詳細記述

書誌詳細
主要な著者: Benjamin M. Janus, Nydia van Dyk, Xuelian Zhao, Katie A. Howell, Cinque Soto, M. Javad Aman, Yuxing Li, Thomas R. Fuerst, Gilad Ofek
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2018-09-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-018-06113-4