Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop
The Ebola virus glycoprotein is a target for cross-protective antibodies. Here, Janus et al. report the crystal structure of the antigen-binding fragment of a pan-reactive antibody bound to a conserved epitope of the glycoprotein, facilitating rational design of cross-protective vaccines and therape...
主要な著者: | , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Nature Portfolio
2018-09-01
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シリーズ: | Nature Communications |
オンライン・アクセス: | https://doi.org/10.1038/s41467-018-06113-4 |