PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging

PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging

The development of novel PET imaging agents for synaptic vesicle glycoprotein 2A (SV2A) allowed for the in vivo detection of synaptic density changes, which are correlated with the progression and severity of a variety of neuropsychiatric diseases. While multiple ongoing clinical investigations usin...

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Bibliographic Details
Main Authors: Takuya Toyonaga, Arman Fesharaki-Zadeh, Stephen M. Strittmatter, Richard E. Carson, Zhengxin Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neuroscience
Subjects:
SV2A
brain PET
small animal
synapse
neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.787404/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.787404/full

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