Asynchronous division at 4–8-cell stage of preimplantation embryos affects live birth through ICM/TE differentiation

Abstract To improve the performance of assisted reproductive technology, it is necessary to find an indicator that can identify and select embryos that will be born or be aborted. We searched for indicators of embryo selection by comparing born/abort mouse embryos. We found that asynchronous embryos...

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Bibliographic Details
Main Authors: Daisuke Mashiko, Zenki Ikeda, Mikiko Tokoro, Yu Hatano, Tatsuma Yao, Tetsuya J. Kobayashi, Noritaka Fukunaga, Yoshimasa Asada, Kazuo Yamagata
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13646-8