Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis

Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis

Abstract Background Cellular changes described in human gastroparesis have revealed a role for immune dysregulation, however, a mechanistic understanding of human gastroparesis and the signaling pathways involved are still unclear. Methods Diabetic gastroparetics, diabetic non-gastroparetic controls...

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Bibliographic Details
Main Authors: Madhusudan Grover, Simon J. Gibbons, Asha A. Nair, Cheryl E. Bernard, Adeel S. Zubair, Seth T. Eisenman, Laura A. Wilson, Laura Miriel, Pankaj J. Pasricha, Henry P. Parkman, Irene Sarosiek, Richard W. McCallum, Kenneth L. Koch, Thomas L. Abell, William J. Snape, Braden Kuo, Robert J. Shulman, Travis J. McKenzie, Todd A. Kellogg, Michael L. Kendrick, James Tonascia, Frank A. Hamilton, Gianrico Farrugia, the NIDDK Gastroparesis Clinical Research Consortium (GpCRC)
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Medical Genomics
Subjects:
Diabetes mellitus
Next generation sequencing
Macrophages
RNA
Signaling
Online Access:http://link.springer.com/article/10.1186/s12920-018-0379-1

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http://link.springer.com/article/10.1186/s12920-018-0379-1

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