Selecting probiotics with the abilities of enhancing GLP-1 to mitigate the progression of type 1 diabetes in vitro and in vivo

We hypothesized that probiotics can stimulate enteroendocrine cells to secret glucagon-like peptide-1 (GLP-1) to mitigate the development of type 1 diabetes (T1D). We thus first established a novel screening platform by coculturing lactic acid bacteria with murine enteroendocrine STC-1 cells. Two st...

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Bibliographic Details
Main Authors: Shih-Hung Wei, Yen-Po Chen, Ming-Ju Chen
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615004004