A Preclinical Model of Computerized Cognitive Training: Touchscreen Cognitive Testing Enhances Cognition and Hippocampal Cellular Plasticity in Wildtype and Alzheimer’s Disease Mice

A Preclinical Model of Computerized Cognitive Training: Touchscreen Cognitive Testing Enhances Cognition and Hippocampal Cellular Plasticity in Wildtype and Alzheimer’s Disease Mice

With the growing popularity of touchscreen cognitive testing in rodents, it is imperative to understand the fundamental effects exposure to this paradigm can have on the animals involved. In this study, we set out to assess hippocampal-dependant learning in the APP/PS1 mouse model of Alzheimer’s dis...

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Bibliographic Details
Main Authors: Amy Shepherd, Tracy Zhang, Lucas B. Hoffmann, Ariel M. Zeleznikow-Johnston, Leonid Churilov, Anthony J. Hannan, Emma L. Burrows
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
touchscreen
mice
cognitive enhancer
Alzheimer’s disease
APP/PS1
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.766745/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2021.766745/full

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