Regulating voltage-gated ion channels with nanobodies
In this work, Morgenstern and colleagues describe an approach involving functionalized nanobodies which decrease the activity of voltage-gated Ca2+ channels associated with β1 subunits and promote their removal from the surface membrane of neurons and muscle.
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Format: | Artikel |
Sprache: | English |
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Nature Portfolio
2022-12-01
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Schriftenreihe: | Nature Communications |
Online Zugang: | https://doi.org/10.1038/s41467-022-35027-5 |