Impact of SARS-CoV-2 vaccination on FcγRIIIA/CD16 dynamics in Natural Killer cells: relevance for antibody-dependent functions

Impact of SARS-CoV-2 vaccination on FcγRIIIA/CD16 dynamics in Natural Killer cells: relevance for antibody-dependent functions

IntroductionNatural Killer (NK) cells contribute to the protective effects of vaccine-induced antibodies thanks to the low affinity receptor for IgG, FcγRIIIA/CD16, whose aggregation leads to the killing of infected cells and IFNγ release, through which they potentiate adaptive immune responses.Meth...

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Bibliographic Details
Main Authors: Cristina Capuano, Davide De Federicis, Daniel Ciuti, Ombretta Turriziani, Antonio Angeloni, Emanuela Anastasi, Giuseppe Giannini, Francesca Belardinilli, Rosa Molfetta, Domenico Alvaro, Gabriella Palmieri, Ricciarda Galandrini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2 vaccine
NK cells
CD16
ADCC
IFNγ
memory NK cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285203/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285203/full

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