Revisiting the Neuroblastoma Cell-Based Assay (CBA-N2a) for the Improved Detection of Marine Toxins Active on Voltage Gated Sodium Channels (VGSCs)

The neuroblastoma cell-based assay (CBA-N2a) is widely used for the detection of marine biotoxins in seafood products, yet a consensus protocol is still lacking. In this study, six key parameters of CBA-N2a were revisited: cell seeding densities, cell layer viability after 26 h growth, MTT incubatio...

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Bibliographic Details
Main Authors: Jérôme Viallon, Mireille Chinain, Hélène Taiana Darius
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/5/281