Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation

Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation

HuR is an abundant RNA-binding protein acting as a post-transcriptional regulator of many RNAs including mRNAs encoding inflammatory mediators, cytokines, death signalers and cell cycle regulators. In the context of intestinal pathologies, elevated HuR is considered to enhance the stability and the...

Full description

Bibliographic Details
Main Authors: Eleni Christodoulou-Vafeiadou, Fotis Ioakeimidis, Margarita Andreadou, Giorgos Giagkas, George Stamatakis, Martin Reczko, Martina Samiotaki, Anastasios D. Papanastasiou, Ioannis Karakasiliotis, Dimitris L. Kontoyiannis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
cytokine regulation
intestinal inflammation and cancer
post-transcriptional regulation
inflammatory bowel disease
animal models of human disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02732/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02732/full

Similar Items