Soluble Factors from Multipotent Mesenchymal Stromal Cells have Antinecrotic Effect on Cardiomyocytes in Vitro and Improve Cardiac Function in Infarcted Rat Hearts

The mechanisms underlying the functional improvement after injection of multipotent mesenchymal stromal cells (MSCs) in infarcted hearts remain incompletely understood. The aim of this study was to investigate if soluble factors secreted by MSCs promote cardioprotection. For this purpose, conditione...

Full description

Bibliographic Details
Main Authors: P. Fidelis-De-Oliveira, J. P. S. Werneck-De-Castro, V. Pinho-Ribeiro, B. C. M. Shalom, J. H. Nascimento-Silva, R. H. Costa e Souza, I. S. Cruz, R. R. Rangel, R. C. S. Goldenberg, A. C. Campos-De-Carvalho
Format: Article
Language:English
Published: SAGE Publishing 2012-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X623916