The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome (ARDS) is a critical illness complication that is associated with high mortality. ARDS is documented in severe cases of COVID-19. No effective pharmacological treatments for ARDS are currently available. Dysfunctional immune responses and pulmonary and systemic in...

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Main Authors: Pamela Nithzi Bricher Choque, Rodolfo P. Vieira, Luis Ulloa, Caren Grabulosa, Maria Claudia Irigoyen, Katia De Angelis, Ana Paula Ligeiro De Oliveira, Kevin J. Tracey, Valentin A. Pavlov, Fernanda Marciano Consolim-Colombo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.624895/full