Dietary Curcumin Ameliorates Aging-Related Cerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway

Dietary Curcumin Ameliorates Aging-Related Cerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway

Background/Aims: Age-related cerebrovascular dysfunction contributes to stroke, cerebral amyloid angiopathy, cognitive decline and neurodegenerative diseases. One pathogenic mechanism underlying this effect is increased oxidative stress. Up-regulation of mitochondrial uncoupling protein 2 (UCP2) pla...

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Bibliographic Details
Main Authors: Yunfei Pu, Hexuan Zhang, Peijian Wang, Yu Zhao, Qiang Li, Xing Wei, Yuanting Cui, Jing Sun, Qianhui Shang, Daoyan Liu, Zhiming Zhu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Curcumin
Cerebrovascular dysfunction
Uncoupling protein 2
5’-AMP activated protein kinase
Aging
Online Access:http://www.karger.com/Article/FullText/354516

Internet

http://www.karger.com/Article/FullText/354516

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