Codon-level information improves predictions of inter-residue contacts in proteins by correlated mutation analysis

Methods for analysing correlated mutations in proteins are becoming an increasingly powerful tool for predicting contacts within and between proteins. Nevertheless, limitations remain due to the requirement for large multiple sequence alignments (MSA) and the fact that, in general, only the relative...

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Bibliographic Details
Main Authors: Etai Jacob, Ron Unger, Amnon Horovitz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/08932