Investigating the Correspondence of Clinical Diagnostic Grouping With Underlying Neurobiological and Phenotypic Clusters Using Unsupervised Machine Learning

Many brain-based disorders are traditionally diagnosed based on clinical interviews and behavioral assessments, which are recognized to be largely imperfect. Therefore, it is necessary to establish neuroimaging-based biomarkers to improve diagnostic precision. Resting-state functional magnetic reson...

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Bibliographic Details
Main Authors: Xinyu Zhao, D. Rangaprakash, Bowen Yuan, Thomas S. Denney Jr, Jeffrey S. Katz, Michael N. Dretsch, Gopikrishna Deshpande
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Applied Mathematics and Statistics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fams.2018.00025/full