Effect of intratumoral application of methotrexate in vivo on frequency of micronuclei in peripheral blood lymphocytes

BACKGROUND: Methotrexate is a cytostatic drug belonging to the group of antimetabolites; it is an antagonist of folic acid with an intensive application in gynecology practice. METHODS: The frequency of micronuclei (MN) in peripheral blood lymphocytes of 30 patients with myoma uteri was analyzed bef...

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Bibliographic Details
Main Authors: Novaković Tanja, Milošević-Đorđević Olivera M., Grujičić Darko V., Marinković Dragoslav M., Janković Slobodan, Arsenijević Slobodan N.
Format: Article
Language:English
Published: Institute of Oncology, Sremska Kamenica, Serbia 2003-01-01
Series:Archive of Oncology
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-7310/2003/0354-73100301001N.pdf