Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis

Background Elevated blood pressure is a major cause of cardiovascular morbidity and mortality. However, it is not known whether midlife blood pressure affects later life cardiovascular risk independent of later life blood pressure. Methods and Results Using genetic association estimates from the UK...

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Bibliographic Details
Main Authors: Dipender Gill, Marios K. Georgakis, Verena Zuber, Ville Karhunen, Stephen Burgess, Rainer Malik, Martin Dichgans
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.016773