Contribution of machine learning to tumor growth inhibition modeling for hepatocellular carcinoma patients under Roblitinib (FGF401) drug treatment

Abstract Machine learning (ML) opens new perspectives in identifying predictive factors of efficacy among a large number of patients’ characteristics in oncology studies. The objective of this work was to combine ML with population pharmacokinetic/pharmacodynamic (PK/PD) modeling of tumor growth inh...

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Bibliographic Details
Main Authors: Mélanie Wilbaux, David Demanse, Yi Gu, Astrid Jullion, Andrea Myers, Vasiliki Katsanou, Christophe Meille
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12831