The Structural Basis of Peptide Binding at Class A G Protein-Coupled Receptors

The Structural Basis of Peptide Binding at Class A G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) represent the largest membrane protein family and a significant target class for therapeutics. Receptors from GPCRs’ largest class, class A, influence virtually every aspect of human physiology. About 45% of the members of this family endogenously bind flexible pe...

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Bibliographic Details
Main Authors: Oanh Vu, Brian Joseph Bender, Lisa Pankewitz, Daniel Huster, Annette G. Beck-Sickinger, Jens Meiler
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
peptide GPCR
class A GPCR
peptide docking
non-canonical amino acids
Online Access:https://www.mdpi.com/1420-3049/27/1/210

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https://www.mdpi.com/1420-3049/27/1/210

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