Molecular Modeling, Synthesis, and preliminary pharmacological evaluation of New Sulfonamide Derivatives as Selective Carbonic Anhydrase XII and IX inhibitors (Research)
New benzene sulfonamide compounds 4–10 was modeled at the molecular level to reveal binding opportunities, bond length, angle, and energy scores in the CA II, CAXII, and CAIX active sites. To test their cytotoxic effect against the AMJ-13 Iraqi breast cancer cell line, researchers synthesized the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy / Mustansiriyah University
2024-04-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1055 |