LY6/PLAUR domain containing 3 (LYPD3) maintains melanoma cell stemness and mediates an immunosuppressive microenvironment

LY6/PLAUR domain containing 3 (LYPD3) maintains melanoma cell stemness and mediates an immunosuppressive microenvironment

Abstract Background Malignant melanoma is a highly heterogeneous skin cancer with the highest mortality rate among dermatological cancers. Catenins form functional networks in the nucleus to regulate gene expression and determine cell fate. Dysregulation of catenin expression correlates with the mal...

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Bibliographic Details
Main Authors: Yi-dou Hu, Ke Wu, Yuan-jie Liu, Qian Zhang, Hui Shen, Jin Ji, Dong Fang, Song-yang Xi
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Biology Direct
Subjects:
Melanoma
Catenin
Cancer stem cell
LYPD3
Immunotherapy
Glycolysis
Online Access:https://doi.org/10.1186/s13062-023-00424-3

Internet

https://doi.org/10.1186/s13062-023-00424-3

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