Endogenous estradiol contributes to vascular endothelial dysfunction in premenopausal women with type 1 diabetes

Endogenous estradiol contributes to vascular endothelial dysfunction in premenopausal women with type 1 diabetes

Abstract Background Endogenous estrogen is cardio-protective in healthy premenopausal women. Despite this favorable action of estrogen, animal models depict a detrimental effect of estradiol on vascular function in the presence of diabetes. The present study sought to determine the role of endogenou...

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Bibliographic Details
Main Authors: Abigayle B. Simon, Cassandra C. Derella, Marsha Blackburn, Jeffrey Thomas, Lawrence C. Layman, Matthew S. Nicholson, Jennifer Waller, Ahmed Elmarakby, Karim M. Saad, Ryan A. Harris
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cardiovascular Diabetology
Subjects:
Diabetes
Endothelial function
Estrogen
Oral contraceptives
Online Access:https://doi.org/10.1186/s12933-023-01966-6

Internet

https://doi.org/10.1186/s12933-023-01966-6

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