The Synthesis of a Pyrazol Analogon of Porphobilinogen with the Help of the Mukaiyama Aldol Reaction

The synthesis of a pyrazol analogon of porphobilinogen is described. The Mukaiyama crossed aldol reaction is the key step of our approach. The retrosynthetic analysis follows the mechanism for the biosynthesis of porphobilinogen initially proposed by Shemin.

Bibliographic Details
Main Authors: André Chaperon, Hugo Bertschy, Anne-Laurence Franz-Schrumpf, Bertrand Hugelet, Antonia Neels, Helen Stoeckli-Evans, Reinhard Neier
Format: Article
Language:deu
Published: Swiss Chemical Society 2003-10-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/3750