Multi-functions of exonuclease 1 in DNA damage response and cancer susceptibility
Exonuclease 1 (EXO1) can catalyze nucleotide chain excision with its conserved N-terminal domain of 5′ to 3′ exonuclease activity, enabling it to influence diverse biological processes facing the challenges of genotoxic environmental factors such as ionizing radiation. This nuclease activity enables...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-12-01
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| Series: | Radiation Medicine and Protection |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666555721000551 |