Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis

Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis

IntroductionAmong immune cells, activated monocytes play a detrimental role in chronic and viral-induced inflammatory pathologies, particularly in Juvenile Idiopathic Arthritis (JIA), a childhood rheumatoid arthritis (RA) disease. The uncontrolled activation of monocytes and excessive production of...

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Bibliographic Details
Main Authors: Nassima Bekaddour, Nikaïa Smith, Benoit Beitz, Alba Llibre, Tom Dott, Anne Baudry, Anne-Sophie Korganow, Sébastien Nisole, Richard Mouy, Sylvain Breton, Brigitte Bader-Meunier, Darragh Duffy, Benjamin Terrier, Benoit Schneider, Pierre Quartier, Mathieu P. Rodero, Jean-Philippe Herbeuval
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
monocytes
cytokines
arthritis
inflammation
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178172/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178172/full

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