MeltR software provides facile determination of nucleic acid thermodynamics

Thermodenaturation (melting) curves of macromolecules are used to determine folding thermodynamic parameters. Notably, this insight into RNA and DNA stability underlies nearest neighbor theory and diverse structure prediction tools. Analysis of UV-detected absorbance melting curves is complex and mu...

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Bibliographic Details
Main Authors: Jacob P. Sieg, Sebastian J. Arteaga, Brent M. Znosko, Philip C. Bevilacqua
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biophysical Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2667074723000022