MeltR software provides facile determination of nucleic acid thermodynamics
Thermodenaturation (melting) curves of macromolecules are used to determine folding thermodynamic parameters. Notably, this insight into RNA and DNA stability underlies nearest neighbor theory and diverse structure prediction tools. Analysis of UV-detected absorbance melting curves is complex and mu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Biophysical Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667074723000022 |