Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection

Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection

Visceral leishmaniasis (VL) is a vector-borne infectious disease that can be potentially fatal if left untreated. In Brazil, it is caused by Leishmania infantum parasites. Blood transcriptomics allows us to assess the molecular mechanisms involved in the immunopathological processes of several clini...

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Bibliographic Details
Main Authors: Sandra Regina Maruyama, Carlos Alessandro Fuzo, Antonio Edson R. Oliveira, Luana Aparecida Rogerio, Nayore Tamie Takamiya, Gabriela Pessenda, Enaldo Vieira de Melo, Angela Maria da Silva, Amélia Ribeiro Jesus, Vanessa Carregaro, Helder I. Nakaya, Roque Pacheco Almeida, João Santana da Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
blood transcriptomics
human visceral leishmaniasis
Leishmania infantum (syn. Leishmania chagasi)
mRNA sequencing (mRNA-seq)
long noncoding RNA–mRNA coexpression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.784463/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.784463/full

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