Utility of Claudin-3 in extracellular vesicles from human bile as biomarkers of cholangiocarcinoma

Utility of Claudin-3 in extracellular vesicles from human bile as biomarkers of cholangiocarcinoma

Abstract Extracellular vesicles (EVs) are released from all cells. Bile directly contacts bile duct tumor; bile-derived EVs may contain high concentrations of cancer biomarkers. We performed a proteomic analysis of human bile-derived EVs and identified a novel biomarker of cholangiocarcinoma (CCA)....

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Bibliographic Details
Main Authors: Chisaki Ikeda, Hiroaki Haga, Naohiko Makino, Tatsutoshi Inuzuka, Ayako Kurimoto, Toshiki Ueda, Akiko Matsuda, Yasuharu Kakizaki, Tetsuya Ishizawa, Toshikazu Kobayashi, Shinpei Sugahara, Michihiko Tsunoda, Kensei Suda, Yoshiyuki Ueno
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81023-y

Internet

https://doi.org/10.1038/s41598-021-81023-y

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