RBD and Spike DNA-Based Immunization in Rabbits Elicited IgG Avidity Maturation and High Neutralizing Antibody Responses against SARS-CoV-2

RBD and Spike DNA-Based Immunization in Rabbits Elicited IgG Avidity Maturation and High Neutralizing Antibody Responses against SARS-CoV-2

Neutralizing antibodies (nAbs) are a critical part of coronavirus disease 2019 (COVID-19) research as they are used to gain insight into the immune response to severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infections. Among the technologies available for generating nAbs, DNA-b...

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Bibliographic Details
Main Authors: Hernan H. M. da Costa, Diego J. B. Orts, Andrew D. Moura, Amaro N. Duarte-Neto, Cinthya S. Cirqueira, Rodrigo A. Réssio, Cristina T. Kanamura, Karen Miguita, Jerenice E. Ferreira, Raimunda T. M. Santos, Patricia P. Adriani, Jair P. Cunha-Junior, Renato M. Astray, Regina M. Catarino, Marcelo Lancelotti, Carlos R. Prudencio
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
SARS-CoV-2
COVID-19
DNA immunization
avidity
soroneutralization
antibody response
Online Access:https://www.mdpi.com/1999-4915/15/2/555

Internet

https://www.mdpi.com/1999-4915/15/2/555

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