Analysis of KRAS, NRAS, and BRAF Mutations, Microsatellite Instability, and Relevant Prognosis Effects in Patients With Early Colorectal Cancer: A Cohort Study in East Asia

Analysis of KRAS, NRAS, and BRAF Mutations, Microsatellite Instability, and Relevant Prognosis Effects in Patients With Early Colorectal Cancer: A Cohort Study in East Asia

BackgroundEarly colorectal cancer (ECRC) refers to any size of colorectal cancer (CRC) whose depth of invasion is limited to the mucosa and submucosa. About 10% of patients with ECRC die from cancer after surgery. KRAS, NRAS, and BRAF mutations and microsatellite instability (MSI) are considered dia...

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Bibliographic Details
Main Authors: Yang Li, Jun Xiao, Tiancheng Zhang, Yanying Zheng, Hailin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
KRAS
NRAS
BRAF
microsatellite instability
gene mutation
early colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.897548/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.897548/full

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