Adaptive designs in critical care trials: a simulation study
Abstract Background Adaptive clinical trials are growing in popularity as they are more flexible, efficient and ethical than traditional fixed designs. However, notwithstanding their increased use in assessing treatments for COVID-19, their use in critical care trials remains limited. A better under...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-023-02049-6 |