Increased nociceptive behaviors and spinal c-Fos expression in the formalin test in a rat repeated cold stress model

Repeated cold stress (RCS) can trigger the development of fibromyalgia (FM)-like symptoms, including persistent deep-tissue pain, although nociceptive changes to the skin have not been fully characterized. Using a rat RCS model, we investigated nociceptive behaviors induced by noxious mechanical, th...

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Bibliographic Details
Main Authors: Teruaki Nasu, Riku Kainuma, Hiroki Ota, Kazue Mizumura, Toru Taguchi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Neuroscience Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0168010223001347